About Help FAQ

Symbol
Name
ID

Brca1
breast cancer 1, early onset
MGI:104537

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes	Abnormality of blood and blood-forming tissues	Anemia	Pyridoxine-responsive sideroblastic anemia	Leukopenia	Thrombocytopenia	Myelodysplasia	Hepatosplenomegaly
Disease(s) Associated with BRCA1	Abnormality of blood and blood-forming tissues	Anemia	Pyridoxine-responsive sideroblastic anemia	Leukopenia	Thrombocytopenia	Myelodysplasia	Hepatosplenomegaly
Fanconi anemia
pancreatic cancer

Mouse Phenotypes		decreased T cell proliferation	decreased thymocyte number	increased double-negative T cell number	decreased double-positive T cell number	abnormal T cell number	decreased single-positive T cell number
Availability	Mouse Genotype
	Brca1^tm2Mak/Brca1^tm2Mak Tg(Lck-cre)548Jxm/? (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23